Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep255 | Calcium & Vitamin D metabolism | ECE2017

Is there a threshold of Vitamin D sufficiency that can prevent secondary hyperparathyroidism?

Amaral Andre , Nunes Tatiana , Anselmo Joao , Cesar Rui

While nonskeletal benefits of vitamin D remain a matter o debate, its importance in bone health is known for decades. Secondary hyperparathyroidism is considered to play a significant role in the pathogenesis of age-related bone loss. In the present study we investigate the association between serum PTH, 25-hydroxyvitamin (25(OH)D) and other clinically related variables in a cross sectional sample of patients followed in an Endocrine consultation during the year 2016. Patients...

ea0037ep709 | Pituitary: basic and neuroendocrinology | ECE2015

Triiodothyronine inhibits TSH secretion through a non-genomic mechanism

Bargi-Souza Paula , Goulart-Silva Francemilson , Rendon Luis M , Fioderlisio Tatiana , Nunes Maria Tereza

TSH is the main regulator of the thyroid hormones (THs) synthesis/secretion, which in turn exert a negative feedback mechanism on the Tshb mRNA expression in the pituitary gland by reducing their transcription rate. Some of triiodothyronine (T3) effects are also shown in short period of time, characterizing the non genomic actions of THs. It has been shown previously that T3 acts on posttranscriptional steps of TSH synthesis and reduces its secre...